γ-Glutamyl transpeptidase in rat mammary tissue. Activity during lactogenesis and regulation by prolactin
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چکیده
منابع مشابه
glutamyl transpeptidase activity and neonatal jaundice
Davidson, D. C., McIntosh, W. B., and Ford, J. A. (1976). Archives of Disease in Childhood, 51, 286. Cord y glutamyl transpeptidase activity and neonatal jaundice. y Glutamyl transpeptidase (GGT) activity was measured in normal neonates and in maternal serum post partum. Levels were above the normal adult range (35I U/l) in all neonates and a significant correlation was found between enzyme act...
متن کاملExpression and regulation of γ-glutamyl transpeptidase-related enzyme in tracheal cells.
Glutathione plays an essential role in protecting the pulmonary system from toxic insults. γ-Glutamyl transpeptidase-related enzyme (GGT-rel) is a novel protein capable of cleaving the γ-glutamyl peptide bond of glutathione and of converting leukotriene C4 to leukotriene D4. A rat homologue of GGT-rel was identified and was found to be highly expressed in cultures of differentiating rat trachea...
متن کاملDiabetic and non-diabetic human cornea and tear γ-glutamyl transpeptidase activity
BACKGROUND Diabetes-related eye disease is due in part to oxidative stress. Gamma-glutamyl transpeptidase (GGT) is a γ-glutamyl cycle enzyme that protects against oxidative stress via glutathione recapture. This study investigates corneal and Schirmer tears GGT activity in diabetic and non-diabetic adults aged 50 to 83 years old. METHODS GGT activity was determined by colorimetric assay on 50...
متن کامل1α,25-Dihydroxyvitamin D3 enhances γ-glutamyl transpeptidase activity in LLC-PK1 porcine kidney epithelial cells.
Mammalian γ-glutamyl transpeptidase (GGT) is expressed most highly in the kidney and serves to recover the constituent amino acids of glutathione in the proximal tubules. Serum GGT is used as a marker for obstructive jaundice and alcoholic liver disease and it has been reported that urinary GGT is a potential marker for bone resorption. The present study investigated the effect of derivatives o...
متن کاملMonoclonal antibodies against rat kidney gamma-glutamyl transpeptidase show species and tissue specificity.
Monoclonal antibodies have been raised against rat kidney gamma-glutamyl transpeptidase (GGT). All five antibodies immunoprecipitate enzyme activity from solubilized kidney brush-border membranes, but not from hepatocellular carcinoma membranes. Three of the antibodies react immunohistochemically with brush-border membranes in sections of adult rat kidney, but none of the antibodies cross-react...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1980
ISSN: 0306-3283
DOI: 10.1042/bj1880565